Mode of action:
Generic RU-486 majorly disrupts pregnancy by causing decidual necrosis. Decidual necrosis is the medical term for the rupture of the thickened uterus lining as a result of pregnancy. It also induces myometrial contractions in the uterus and cervical softening. All of this combined with the effects of misoprostol leads to the expulsion of pregnancy contents.
RU-486 is also known to exhibit anti-glucocorticoid and mild antiandrogenic activity.
Regimen:
On day one, swallow 200 mg (one tablet) of Generic RU-486 with water (a single oral dose). Do not forget to take the secondary medication with the specified dosage within 24-48 hours of this pill. Follow the restrictions on food, beverages and activity.
Kindly note that this medication doesn’t suit all cases and does have a few contraindications.
Expected symptoms:
You might experience vaginal bleeding within the first two days of mifepristone intake. This may however not begin immediately. One might also expect mild cramps although it is more prominent after the second pill.
In 3 out of every hundred women, complete termination of pregnancy occurs at this very stage. It is indicated by the expulsion of pregnancy components without any blood. Ensure confirmation of this condition through formal clinical assessments.
Common side-effects:
- Nausea
- Irregular bowel movements
- Cramping
- Fatigue
- Chills and fever
- Dizziness
- Breast tenderness
- Skin rashes
Precautions:
This medication cannot be recommended in the following cases
- You are over 10 weeks pregnant
- Your pregnancy is ectopic
- You are allergic to the components of the medicines
- You have certain conditions of the heart, liver or lungs or adrenal failure
- You have been smoking or drinking excessively
- You are under other over-the-counter medication
- You are a breastfeeding woman
In rare cases, complications may occur. Should there be extreme discomfort, please visit a doctor.
